Magnolia Officinal P.E. 2-98%,Honokiol 98%,Magnolol 98%,Magnolia bark powder
2%,25%,50%，90%,95%98%
Colore: white powder
Source: Magnolia bark
Test: HPLC
Price: USD 80.00/kg
MOQ: 1 kg
Name: Honokiol
IUPAC name: 2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol
Other names: houpa, hnk
Active ingredient: Honokiol
Molecular formula :C18H18O2
Molar mass :266.334 g/mol
Appearance :White solid
[CAS Number] 528-43-8 Solubility in water: sparingly (25 °C)
Magnolia Species and Traditional Use
While magnolia species have been incorporated in traditional healing systems throughout the world, the barks of Chinese M. officinalis and Japanese M. obuvata have become quite popular due to their verified levels of phytochemicals like honokiol. The bark of M. officinale (houpa) is often sought for incorporation in traditional Chinese formulas addressing “chi stagnation”, asthma, anxiety, cancer, and digestive disorders.
China produces well over 200 tons of magnolia bark a year. With its popularity comes the concern of over-harvesting since the tree is killed during bark procurement. A positive side to this is that the honokiol molecule is not very complex and is easily synthesized through organic chemistry methods.
Pharmokinetics
Honokiol appears to be non toxic, easily absorbed, and systematically available. This is important since many promising materials like Epigallocatechin Gallate (EGCG) are not absorbed well in the digestive tract. Honokiol also avoids immediate clearing by the liver (first pass effect) and crosses blood barriers that often exclude other compounds.Honokiol has a significant, long-lasting central muscle relaxation, inhibition of the central nervous system, anti-inflammatory, antibacterial, disease of the original microbial, anti-ulcer, anti-oxidation, anti-tumor, morphine withdrawal response, inhibit platelet aggregation and other pharmacological effects for the treatment of acute enteritis. bacterial or amoebic dysentery. chronic gastritis. Among them, the antibacterial effect of magnolol on the Gram-positive bacteria, acid-resistant bacteria, filamentous fungi have significant antimicrobial activity, a more significant antibacterial effect on Streptococcus mutans, the strongest inhibitory effect on Staphylococcus aureus. Clinically for the elimination of the chest and abdomen full of nausea, sedation central nervous system, athletes, muscle relaxants, anti-fungal, anti-ulcer drugs
Recent studies have explored honokiol and found validation for it as a treatment option for anxiety, cancer, peridontal disease, stroke, inflammation, and even weight loss.
Physical properties
This product is tan to white fine powder, gas smell, taste spicy, slightly bitter flavor. The monomer is a colorless needle crystal (water), melting point 102 ° C. Soluble in benzene, ether, chloroform, acetone and common organic solvents, insoluble in water, soluble in dilute solution of caustic soda to get sodium. Phenolic hydroxyl group susceptible to oxidation, allyl is easy to carry out the addition reaction.
Application of formulations
Suppositories, lotions, tablets, capsules, and so on.
Product storage: Store in a cool, dry, dark, avoid heat
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