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top quality U-47700,Alprazolam Email: sales1@hbmilin.com Skype：live:a570790caebb92c5
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Skype：live:a570790caebb92c5
Email: sales1@hbmilin.com
Product Name: U-47700
CAS: 121348-98-9
Molecular Formula:?C16H22Cl2N2O
Molar Mass: 329.27 g·mol?1
Purity:?99%min.
Appearance:?White Powder
Application:?research
Delivery Time:?within 3-5 hours after receipt of payment
Package:?foil bag or Customized
Production Capacity:?100 Kilogram/Month
Storage:?Store in Cool and dry .place, keep away fire.
Transportation:?air express delivery?
Payment :?Money Gram, Western Union, T/T
MOQ:?10 Gram
U-47700 is an opioid analgesic drug developed by a team at Upjohn in the 1970s that acts as a selective agonist of the u-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the k-opioid receptor and has around 7.5 x the potency of morphine in animal models.
3. character
U-47700 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure-activity relationship of the scaffold.
Upjohn looked for the key moieties which gave the greatest activity[8] and posted over a dozen patents on related compounds, each optimizing one moiety] until they discovered that U-47700 was the most active.
U-47700 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research.
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