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Paclitaxel injection 5ml:30mg anti-cancer antineoplastic& quot; or & quot;cytotoxic plant alkaloid intravenous u

5ml:30mg

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Description

Paclitaxel injection 5ml:30mg anti-cancer antineoplastic& quot; or & quot;cytotoxic plant alkaloid intravenous use human albumin
Composition:
Each vial contains Paclitaxel 30mg.
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What Paclitaxel Is Used For:
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Treatment of breast, ovarian, lung, bladder, prostate, melanoma, esophageal, as well as other types of solid tumor cancers. It has also been used in Kaposi& acute;s sarcoma.
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Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.
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How Paclitaxel Is Given:
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Paclitaxel is given as an injection or infusion into the vein (intravenous, IV).
Paclitaxel is an irritant. An irritant is a chemical that can cause inflammation of the vein through which it is given. If the medication escapes from the vein it can cause tissue damage. The nurse or doctor who gives
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Paclitaxel must be carefully trained. If you experience pain or notice redness or swelling at the IV site while you are receiving Paclitaxel, alert your health care professional immediately.
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Because severe allergic reactions have occurred in some people taking Paclitaxel, you will be asked to take medications to help prevent a reaction. Your doctor will prescribe the exact regimen.
Paclitaxel is given over various amounts of times and in various schedules.
There is no pill form of Paclitaxel.
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The amount of Paclitaxel and the schedule that it is given will receive depend on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule.
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Paclitaxel Precautions:
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Before starting Paclitaxel treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, or products containing aspirin unless your doctor specifically permits this.
Do not receive any kind of immunization or vaccination without your doctor& acute;s approval while taking Paclitaxel.
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Inform your health care professional if you are pregnant or may be pregnant prior to starting this treatment. Pregnancy category D (Paclitaxel may be hazardous to the fetus. Women who are pregnant or become pregnant must be advised of the potential hazard to the fetus).
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For both men and women: Do not conceive a child (get pregnant) while taking Paclitaxel. Barrier methods of contraception, such as condoms, are recommended. Discuss with your doctor when you may safely become pregnant or conceive a child after therapy.
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Do not breast feed while taking Paclitaxel.
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How Paclitaxel Works:
Cancerous tumors are characterized by cell division, which is no longer controlled as it is in normal tissue. & quot;Normal& quot; cells stop dividing when they come into contact with like cells, a mechanism known as contact inhibition. Cancerous cells lose this ability. Cancer cells no longer have the normal checks and balances in place that control and limit cell division. The process of cell division, whether normal or cancerous cells, is through the cell cycle. The cell cycle goes from the resting phase, through active growing phases, and then to mitosis (division).
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The ability of chemotherapy to kill cancer cells depends on its ability to halt cell division. Usually, the drugs work by damaging the RNA or DNA that tells the cell how to copy itself in division. If the cells are unable to divide, they die. The faster the cells are dividing, the more likely it is that chemotherapy will kill the cells, causing the tumor to shrink. They also induce cell suicide (self-death or apoptosis).
Chemotherapy drugs that affect cells only when they are dividing are called cell-cycle specific. Chemotherapy drugs that affect cells when they are at rest are called cell-cycle non-specific. The scheduling of chemotherapy is set based on the type of cells, rate at which they divide, and the time at which a given drug is likely to be effective. This is why chemotherapy is typically given in cycles.
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Chemotherapy is most effective at killing cells that are rapidly dividing. Unfortunately, chemotherapy does not know the difference between the cancerous cells and the normal cells. The & quot;normal& quot; cells will grow back and be healthy but in the meantime, side effects occur. The & quot;normal& quot; cells most commonly affected by chemotherapy are the blood cells, the cells in the mouth, stomach and bowel, and the hair follicles; resulting in low blood counts, mouth sores, nausea, diarrhea, and/or hair loss. Different drugs may affect different parts of the body.
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Paclitaxel belongs to a class of chemotherapy drugs called plant alkaloids. Plant alkaloids are made from plants. The vinca alkaloids are made from the periwinkle plant (catharanthus rosea). The taxanes are made from the bark of the Pacific Yew tree (taxus). The vinca alkaloids and taxanes are also known as antimicrotubule agents. The podophyllotoxins are derived from the May Apple plant. Camptothecan analogs are derived from the Asian & quot;Happy Tree& quot; (Camptotheca acuminata).
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Podophyllotoxins and camptothecan analogs are also known as topoisomerase inhibitors. The plant alkaloids are cell-cycle specific. This means they attack the cells during various phases of division
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Name of Drug | Paclitaxel injection |
REG.NO. | 020473 | ? |
Mfg. Date | 09/2016 | ? |
Sampling Date | 30/11/2016 | ? |
Specification | 5ML 30mg | ? |
Standards: | USP27 |
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